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Clinicopathologic features of complement activation signatures in colorectal cancer

10.18632/oncotarget.11168 39 PickartL.FreedmanJ.LokerW.PeisachJ.PerkinsC.StenkampR.et al (1980)
Many modern lifestyle factorspoor diet, chronic stress, lack of sleepcontribute to a state of low-grade, chronic systemic inflammation that can make acne much, much worse

This validated the in vitro model as representative of age-related Leydig cell dysfunction

For research requiring minimal systemic effects, AOD9604 may be preferable