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F.AusubelF

No serious adverse events were attributed to AOD-9604

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For instance, although the mitochondrial complex I inhibitor IACS-010759 demonstrated strong anti-leukemia activity in preclinical trials and entered clinical trials, the trials were eventually terminated due to dose-limiting toxicities (DLTS) such as peripheral neuropathy and lactic acidosis

doi: 10.3389/fendo.2019.00575 200 ArancetaJSerra-MajemLRibasLPrez-RodrigoC

Luteolin improves contractile function and attenuates apoptosis following ischemia-reperfusion in adult rat cardiomyocytes
