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With the FDA nod, Lumryz becomes the only FDA-approved once-at-bedtime oxybate treatment for cataplexy and EDS in this patient population

Clinically defined and diagnosed as having a body mass index (BMI) exceeding 30 kg/m 2 , the condition has rapidly risen in the global human population from 4% in 1975 to an astounding 18% (more than quadruple) in 2016

It has decades of randomized controlled trial data behind it and is widely regarded as the reference-standard topical retinoid against which newer molecules are measured

Meanwhile, MR can also downregulate genes involved in an inflammatory response and immune cell infiltration, such as chemokine receptor (CCRs), chemokine ligand 7 (CCL7), IL-1, IL-6, IFN-, and TNF-

It is known to participate in the neutralization of free radicals and reactive oxygen compounds as well as maintain exogenous antioxidants such as vitamins C and E in their active forms [17]

Ethyl Ascorbic Acid or EAC for short is an "etherified derivative of ascorbic acid" that consists of vitamin C and an ethyl group bound to the third carbon position