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Polymeric micelles for pulmonary drug delivery: A comprehensive review

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SPI-1005 is an oral pill developed by Sound Pharmaceuticals to target inflammation and oxidative stress in the inner ear

Pandey et al

However, its natural levels in the body decrease as a result of aging, stress, and toxin exposure

For example, tumor-associated macrophages can secrete certain metabolites that promote tumor cell resistance to ferroptosis, further influencing tumor progression and the effectiveness of immunotherapy (63)
