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Description
Impaired insulin signaling Insulin signaling plays a crucial role in maintaining peripheral nerve health, and its impairment significantly contributes to the pathogenesis of DPN

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In contrast, citrulline supplementation not only resulted in an increase in arginine flux, but also in a greater increase in plasma arginine concentration than arginine supplementation itself

Curr Opin Endocrinol Diabetes Obes (2020) 27:35863

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2020;8 doi: 10.3389/fchem.2020.573297