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Some clinical studies have shown that pioglitazone treatment (30 mg/day, P.O for 4 weeks) exhibits antioxidant properties in diabetic patients, as reflected by a decrease in MDA [218, 219]

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[DOI] [PubMed] [Google Scholar] 101.Arajo M.B., Moura L.P., Junior R.C.V., Junior M.C., Dalia R.A., Sponton A.C., Ribeiro C., Mello M.A.R

In normal cells, however, epitalon led to a significant increase in telomerase activity by fourfold in IBR.3 treated cells compared to untreated, and 26-fold increase in treated HMEC cells compared to untreated