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doi: 10.1089/ten.teb.2010.0370

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The chamber is designed to separate the luminal side from the basolateral side of the epithelium and, to assess permeability, molecules are placed in the luminal chamber, and the flux of these markers to the basolateral side is measured as an indicator of permeability of the epithelium [41]

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Specifically, CD38 acts as an auxiliary factor that further activates downstream signaling pathways that were initially triggered by the CXCR4 and BCR complex