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Although PGC-1-related signaling pathways have been shown to play diverse roles in protecting various types of hearing loss, however, whether these pathways ultimately affect ototoxicity by regulating mitochondrial biogenesis is still unclear, and the mechanisms of PGC-1 in ototoxicity are expected to be investigated in more detail

Comparing the glutathione levels of individuals aged 60-79 with those aged 100-106, it was discovered that centenarians with better health had higher glutathione levels [8]

[DOI] [PMC free article] [PubMed] [Google Scholar] 43.Al-Dabet MM Shahzad K Elwakiel A Sulaj A Kopf S Bock F, et al

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