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The broad and partly overlapping substrate specificity of GSTs (Wtjen and Fritsche, 2010) makes it difficult to explain why some GSTs might be more, or less, expressed in the seal brain

[DOI] [PMC free article] [PubMed] [Google Scholar] 48.Nava R., Zuhl M., Moriarty T., Amorim F., Kelsey C., Welch A., Mccormick J., King K., Mermier C

2f) providing strong evidence that Na + binding is allosterically coupled to carnitine binding

Its relevance to women's health crystallised with the finding that MOTS-c levels decline with age and estrogen depletion correlating directly with reduced skeletal muscle insulin sensitivity and visceral adiposity in postmenopausal women

Oxidation of the cysteine-rich regions of parkin perturbs its E3 ligase activity and contributes to protein aggregation