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These observations underscore the drawbacks of xenograft models

Biomaterials Science

Other classical NRF2 target genes mRNA expression were also investigated by RT-PCR: Heme Oxygenase 1 (HO1) and NAD(P)H Quinone Dehydrogenase 1 (NQO1), and enzymes related to glutathione utilization, such as the Glutathione Peroxidases 1, 2 and 3 (GPx1, GPx2 and GPx3), with all of them having reduced expression in the NCI H23 compared to A549 cells (Supplementary Fig

In the current study, the dose of glutathione was 300 mg/day

[DOI] [PMC free article] [PubMed] [Google Scholar] 25.Speranza L., Pesce M., Patruno A., Franceschelli S., Lutiis M.A., Grilli A., Felaco M