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Figure 4 3.3 Polyphenols in DN Some polyphenols have been widely used to repair molecules after free radical damage and modulate various dysregulated mediators and pathways, such as directly or indirectly blocking the production of ROS and alleviating the process of oxidative stress and inflammatory response, suggesting that polyphenols are an alternative approach to mitigate DN progression

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For this to occur, a marker that predicts patient response to the drug is essential

The Y-Maze was performed as previously described (Darvas et al., 2009)

Niacinamide helps even out skin tone while also supporting the skin barrier and reducing redness