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Nrf2 is generally coupled to Kelch-like ECH-associated protein 1 (Keap1) in an inactive form, and the ubiquitin-proteasome system destroys the complex, allowing cells to maintain a steady low level of Nrf2 (258)

[DOI] [PubMed] [Google Scholar] 212.Lasselin J, Rehman JU, Akerstedt T, Lekander M, Axelsson J
