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Appl Nanosci 5:703709

However, lysosomal dysfunction compromises this clearance mechanism, leading to intraneuronal build-up and aggregation of -synuclein 49

The "reduced" form (GSH) is the active, antioxidant-ready state, whereas the "oxidized" form (GSSG) has already expended its electron and must be recycled by the body

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[DOI] [PMC free article] [PubMed] [Google Scholar] 99.Jiao Y., Yu Y., Li B., Gu X., Xie K., Wang G., Yu Y

They may instead promote base excision repair and non-homologous end joining by increasing repair protein availability or by restricting ROS-mediated base damage
