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Mast cells: new therapeutic target in helminth immune modulation

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Ethics approval and consent to participate The study was carried out in compliance with the Declaration of Helsinki, and the research protocol received approval from the Medical Ethics Committee of Nanfang hospital of Southern Medical University

Broadhurst MJ, Leung JM, Kashyap V, et al

Design of mouse experiments For the calculation of the estimated sample size a power analysis was performed according to the formula: n= 2(Z /2 +Z ) 2 * 2 / 2 , with a power (1-) of 80% and a significance () of 0.05

2.2 The Disulfide Bond Linker Mechanism After the disulfide linker enters the cell, it is degraded in the lysosome, generating cysteine (Cys)-disulfide metabolite