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This discrepancy highlights the need for further research to understand the specific conditions under which blue light may contribute to DE pathogenesis and to identify patient populations that might benefit from blue light filtering interventions

Changes in methionine metabolism and histone H3 trimethylation are linked to mitochondrial defects in multiple sclerosis

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Key points Prevalent triggers of migraine attacks can all be linked to unbalanced cerebral energy metabolism and/or oxidative stress

Mitochondrial respiration and peroxisomal lipid metabolism are the primary sources of H 2 O 2 in eukaryotic cells (47)

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