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Knight P, Heer D, Abdenour G

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The dose curve in saliva has been evaluated according to the previously described protocol

However, not all HDAC subtypes are abnormally expressed in all malignancies, so pan-inhibition of HDAC is not an effective way to treat cancer (191)

For instance, normally, anti-apoptotic Bcl-2 factor causes cell death by inhibiting pro-apoptotic members of the Bcl-2-family in the mitochondria

[DOI] [PubMed] [Google Scholar] 7.Fulceri F., Morelli M., Santocchi E., Cena H., Del Bianco T., Narzisi A., Calderoni S., Muratori F