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Phosphoribosyl diphosphate (PRPP): biosynthesis, enzymology, utilization, and metabolic significance

The multi-target approach to the inner ear underscores the significance of natural products in drug discovery for hearing impairments (Castaneda et al

Epitalon = the synthetic tetrapeptide Ala-Glu-Asp-Gly (AEDG)

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Once opened, it is recommended to consume the product as soon as possible

For MCAS, elevated baseline serum tryptase or urinary histamine metabolites may be helpful