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Alzheimers Disease as Type 3 Diabetes: Common Pathophysiological Mechanisms between Alzheimers Disease and Type 2 Diabetes

CBS is responsible for the production of cystathionine, cysteine and H 2 S in the transsulfuration pathway, all of which are key antioxidant molecules 36

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Cumulative evidence suggests that both direct inhibitors of ferroptosis, i.e., radical-trapping antioxidants, iron-chelating agents, and activators of the System Xc-/GSH/GPX4 axis, and indirect regulators, i.e., natural compounds and dietary supplements, show promise as anti-ferroptotic agents in promoting ocular cell survival

Mitochondrial dysfunction is one of the most prominent features of epilepsy, affecting 35-60% of patients with epilepsy (185)

Besides this, it also switches the production of eumelanin (a dark brown color) to pheomelanin (a yellow-red color), which leads to the lightening of the skin