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Flavonoids are classified into 12 main subclasses according to their chemical structure

Regulation of carbohydrate-responsive metabolic genes by histone acetylation and the acetylated histone reader BRD4 in the gene body region
Further research indicates that this regulatory process is closely related to oxidative stress mediated by ROS and nitric oxide (NO) induced by inflammatory factors: ROS/NO promotes DMT1 expression and inhibits FPN1 function by upregulating iron regulatory protein 1 (IRP1) and hepcidin, ultimately forming a vicious cycle of iron overload-inflammation-iron retention [98]
Oxidative modification of peroxiredoxin is associated with drug-induced apoptotic signaling in experimental models of Parkinson disease

doi: 10.1016/j.it.2012.10.001