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In some instances, a deficiency in B12 may present symptoms similar to hemolytic anemia, including intramedullary hemolysis and elevated levels of lactate dehydrogenase (LDH), which raises concerns about serious conditions like thrombotic microangiopathy (TMA) [3,4]

Subcutaneous injections target the fatty tissue layer between the skin and the muscle

This is because CKD can cause damage to kidneys, making them less able to filter these substances from the blood, which may lead to certain health complications

The AMA is a third-party beneficiary to this Agreement

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Given the emergence of COVID-19 in the second year of the study, trial visits were permitted to be conducted via telephone, during which counseling was provided and safety-related information was collected