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The kidneys normally degrade roughly one-third of circulating insulin, so progressive renal impairment prolongs the half-life of these medications
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Because liraglutide has a 13 to 15 hour half-life, it must be injected daily to maintain effective blood levels
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[DOI] [PMC free article] [PubMed] [Google Scholar] 64.Hernndez-Santos N., Gaffen S.L
