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Biological therapies, especially anti-TNF therapy are effective treatments, but the primary lack of response to TNF inhibitors or the secondary loss of response among some patients requires the search for new therapeutic solutions [121,122,123]

It is of some interest that realgar, a polymorph of arsenic sulphide (As 4 S 4 ), and cinnabar (mercury sulphide) found an ethno-pharmacological use in Chinese medicine [193,194]

In these cases, B12 injections can bypass the digestive system and deliver the vitamin directly into the bloodstream

These growth factors are essential for cell proliferation and differentiation, processes that are crucial for tissue regeneration

Agarose has been widely used for glutathione conjugation

J.FehrenbachG