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Patients with rhinorrhea (rhinitis) who are receiving the intranasal formulations of cyanocobalamin may experience decreased medication absorption secondary to nasal discharge

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And even some meat eaters dont absorb it as well as they might

Maintaining Healthy Skin Focusing on b12 and skin health can lead to noticeable improvements in skin repair and overall appearance

[21] When treated with cyanocobalamin, patients with Leber's disease may develop serious optic atrophy, possibly leading to blindness, based on few case reports

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