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Mosca et al., 2021

This suggests that ginsenoside Rf helps treat EMs by initiating autophagy-dependent ferroptosis (Zhang L

174,175,176 Specifically, DKK1 has been reported to bind to LRP5/6, activate GSK-3, inhibit Wnt/-catenin signaling, and promote neuronal apoptosis by increasing the expression of the pro-apoptotic protein Bax and reducing the expression of the anti-apoptotic protein Bcl-2

K., Palmer J., and Flint S

[DOI] [PMC free article] [PubMed] [Google Scholar] Wu G., Lupton J.R., Turner N.D., Fang Y., Yang S

and the malic enzyme 1 (ME1) that converts pyruvate to malate [30]
