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Mechanical hyperalgesia may also be caused by centrally amplifying responses

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The percentages of participants who submitted any data for the adverse event within seven days after the booster injection or the second dose during the primary series are shown

The BH4 level determines the production rate of these important hormones and neurotransmitters and thus the bodys ability to synthesise neurotransmitters such as dopamine, adrenaline and serotonin

It also shows neuroprotective effects by reducing inflammation, reducing oxidative stress, and inhibiting apoptosis (83, 84)

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