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The following additional adverse reactions have been reported rarely: vitiligo depigmentation, small depigmented spots, hypertrichosis, reddening (signs of keratosis pilaris), and exacerbation of recurrent herpes viral infection (i.e., herpes labialis)

Eggers regression test corroborated this finding, yielding a non-significant intercept (0.20

Uptake into Mouse Brain of Four Compounds Present in the Psychoactive Beverage Kava

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These results highlight that targeting pathways involved in -KG production offers attractive therapeutically opportunities in diseases associated with macrophage malfunction