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[37] A 2024 evidence map of 57 randomized controlled trials of complementary and alternative therapies for genitourinary syndrome of menopause identified 31 trials of 20 different phytoestrogen products, 7 trials of vitamin D or E, and smaller numbers of trials of probiotics, acupuncture, yoga, and cognitive behavioral therapy

doi: 10.1212/01.WNL.0000150588.75281.58

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doi: 10.4103/2230-8210.163172

However, most studies used small sample sizes and lacked long-term follow-up, limiting generalizability

Several users note that they saw similar results after switching to plain tirzepatide with a separate oral L-carnitine supplement, which cost significantly less