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To diagnose the cause of this symptom, a doctor may refer someone to an otolaryngologist

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Absorption can be inhibited by poorly functioning kidneys, cigarette smoke, nitrous oxide used for anaesthesia, heating food in a microwave or cooker and some medications, including Metformin (for diabetes), anticonvulsants and proton pump inhibitors (PPIs)
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Importantly, NNMTi is highly selective and has no inhibitory effect on other SAM-dependent methyltransferases or NAD + salvage pathway enzymes

This is the most important caveat for beginners, and the one most vendor pages omit