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In addition to mitochondria, peroxisomes and plasma membrane NADPH oxidases are other sources of free radicals in cells

In transplantation, cold ischaemia, a surgical technique, involves organs cooling after blood supply has been cut off to reduce the organ metabolism and oxygen consumption, but the subsequent reperfusion contributes to graft dysfunction and rejection [10]

This disorder is closely linked to culturally reinforced masculine ideals, especially in Western societies, where muscularity is associated with strength, dominance, and masculinity

Oxidative modification of CMA substrates increases their susceptibility to degradation, and CMA is enhanced through LAMP2a upregulation in cells challenged with ROS

Patients with thalassemia or sickle cell anemia receive blood transfusions on a regular basis as a treatment technique, which contributes to the same problem of having excess circulatory iron

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