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As mentioned above, selenocysteine is an important amino acid of the GPX4 active sites

Glutathione deficiencies appear to be common in central nervous system diseases (chronic fatigue syndrome, multiple sclerosis, Parkinsons Disease, Alzheimers, autism, depression)

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Antioxidant enzyme activity 34

Slow recovery after physical exercise or long days

Import is thought to be regulated by SLC25A25 (SCaMC-2), a Ca-activated Mg-ATP carrier that also transports zinc