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To clarify gut microbiota interventions' efficacy in alleviating depressive symptoms, researchers did systematic reviews and meta-analyses, including RCT on probiotics, prebiotics, synbiotics or fecal microbiota transplantation in adults (18 years) that used validated, placebo-controlled measures to assess depressive symptoms
In the future, larger amounts of clinical data will be needed to draw more comprehensive and rational conclusions

Where indicated an unpaired t -test was used and significance was accepted at p 4 months
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[DOI] [PubMed] [Google Scholar] 28.Kim JM, Lee JC, Chang N, Chun HS, Kim WK
