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Integration of multiple approaches, e.g

The autophagy initiating kinase ULK1 is regulated via opposing phosphorylation by AMPK and mTOR

The coactivator PGC-1 cooperates with peroxisome proliferator-activated receptor alpha in transcriptional control of nuclear genes encoding mitochondrial fatty acid oxidation enzymes

Statistical analysis The qualitative variables are expressed as percentages and the quantitative variables as median [25th75th percentiles]