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Determination of the molecular orbitals that define redox reactivity To investigate the molecular orbitals that determine the enzymes activity, ground-state and excited-state DFT calculations were performed along with analysis of the HERFD-XANES pre-edge (Fig

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When the hydroxyl group of RNA forms intramolecular hydrogen bonds with phosphate anions, it facilitates the ionization of phosphate groups, thereby enhancing the acidity of RNA