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NF-B activation also contributes to the mesenchymal (MES) transition phenotype associated with treatment resistance and tumor recurrence [72]

The importance of intracellular targeting of cortactin has been shown with a cell-permeable peptide that binds cortactin, and inhibits the invasion of a range of cancers including glioblastomas (Hashimoto et al., 2006)

95% CI, 95% confidence interval

This work shows that at least a fraction of DTP cells slowly replicate, thus countering the idea that the DTP phenotype perfectly aligns with the dormancy state

& Ghasemi, S
