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Hypothesis-driven studies have so far explored coordination between individual proteins and metabolites 3,4

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95 AMPs, predominantly secreted by Paneth cells, are vital for gut homeostasis by controlling pathogenic and commensal bacterial populations

However, PKM2 overexpression in astrocytes promotes excessive aerobic glycolysis, exacerbating inflammatory neuropathic pain

This question has practical implications, since the 1A variant is inactivated more rapidly than the 1C variant

Regulation of peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PGC-1 alpha) and mitochondrial function by MEF2 and HDAC5