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After entering the cochlea, cisplatin is taken up into cells by diffusive and passive transport, copper transporter protein 1 (Ctr1) and organic cation transporter protein 2 (OCT2), endocytosis, and toxicity through DNA adduct formation, oxidative stress, mitochondrial dysfunction, inflammatory response, and ferroptosis (Elmorsy et al., 2024)

Targeted ablation of IKK2 improves skeletal muscle strength, maintains mass, and promotes regeneration

Guo, N., McIntosh, C

[DOI] [PMC free article] [PubMed] [Google Scholar] 42.Schulthei C, Willscher E, Paschold L, Gottschick C, Klee B, Henkes SS, et al

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Dysbiosis in the gut bacterial microbiome of patients with uveitis, an inflammatory disease of the eye