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Oral corticosteroids: This is a systemic therapy that can improve symptoms throughout the body

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Among upstream regulators of ferroptosis in IBD, hypoxia-inducible factors (HIFs) occupy a unique position by integrating hypoxic stress, iron homeostasis, and inflammatory signaling, thereby setting the threshold at which epithelial ferroptosis is triggered

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YBX1 and RPL32 mRNA were positive and negative controls, respectively

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Even so, the frequency and significance of these observations are presently unclear

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