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Adenosine injection is contraindicated in: Second- or third-degree A-V block (except in patients with a functioning artificial pacemaker)

The physiological conditions in which these downstream effectors are either increased or decreased varies as summarized in Fig

On/off cycling here is driven by caution, not by tolerance data: because there is no long-term human safety record, building in scheduled off periods is the conservative research default

The ability of vitamin E to reduce oxidative damage to the brain has been demonstrated in preclinical and clinical human studies

This is often temporary as your body adjusts