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Vascular smooth muscle cells in atherosclerosis

Third, since conditional Slc7a11 knockout mice were unavailable, our in vivo analysis relied on pharmacologic inhibition of the cystine/glutamate transporter and cannot completely exclude off-target effects of sulfasalazine or the contribution of other cell types beyond dendritic cells and fibroblasts in glutathione synthesis

In: von Stechow L, editor

GSSG prevented TNF-induced activation of IKK-, an upstream kinase in the NF-B signaling pathway, by inducing IKK- glutathionylation (IKK--SSG formation)

cruzi Chagas disease

However, the prediction of these markers from the core basic parameters could possibly assist in limiting the necessity for these assays, which are complex, highly expensive and lack universal standardization