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Brain fog

(November 2007)

Metformin activates AMPK through mitochondrial complex I inhibition at a low, steady level

[DOI] [PMC free article] [PubMed] [Google Scholar] 170.Damiani, R

Reports that newborns with a complete lack of insulin effects due to inactivating defects in the INSR gene can now survive for extended time into adolescence when treated with recombinant IGF-I, that stimulate glucose uptake via the IGF1R sharing common signaling pathways with the INSR, support an important direct role of IGF-1 signaling on metabolism (93)
