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[DOI] [PMC free article] [PubMed] [Google Scholar] 51.Han M, et al

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The in vivo experiments were performed with 49 mice for each group

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MTHFR and the Methylation Cycle Normal role: MTHFR converts 5,10-methylene-tetrahydrofolate into 5-methyltetrahydrofolate (5-MTHF), the active folate required for homocysteine methionine conversion

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Understanding these genetic variations is critical in precision medicine, as they affect baseline thyroid function and modulate the efficacy and safety of Se-based interventions [103]

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