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They have typical radiological features with advanced renal dysfunction

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A double-blind randomized controlled trial demonstrated that 24 weeks of taVNS intervention improved scores on multiple cognitive measures, including the Montreal Cognitive Assessment-Basic, Auditory Verbal Learning Test, and Boston Naming Test, with only mild and reversible adverse effects, confirming its clinical safety and efficacy ( Trial (Safety and feasibility of transcutaneous vagus nerve stimulation in mild cognitive impairment) will further evaluate the safety and feasibility of taVNS in 40 participants, providing additional evidence for early intervention in AD ( In summary, current VNS research predominantly focuses on the treatment of PD