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Carnitine deficiency occurs in aberrations of carnitine regulation in disorders such as diabetes, sepsis, cardiomyopathy, malnutrition, cirrhosis, endocrine disorders and with aging

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Significant increase in water and food intake, variations in the absolute and relative weights of seminal vesicles, and effects noted in urinalysis evaluations were all deemed to be of no toxicological significance because they either represented a physiological response, were temporary and disappeared at the end of the recovery phase, or weren't associated with any microscopic alteration