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189 Although DHA is known to slightly elevate LDL levels, high-dose DHA has been shown to increase LDL turnover and LDL particle size 190 (larger LDL particles may not promote atherosclerosis as much as small LDL particles)
Stage 1: Composition of Matter Patent (Years 0-20 from filing) The COM patent covers the active pharmaceutical ingredient itself, its salts, and often its major polymorphs
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doi:10.1016/j.ecl.2021.11.007 Santi D, Cignarelli A, Baldi M, et al
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