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Mozaffarian DEJ, Benjamin AS, Go, et al

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Both the electron transfer systems catalyze the six-electron reduction of sulfite (SO 3 2 ) to sulfide (S 2 ): 3NADPH + SO 3 2 + 3H + 3NADP + + S 2 + 3H 2 O

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2011;29(12) doi: 10.1038/nbt.2073

To date, only one crystal structure of a bacterial membrane-embedded sterol reductase MaSR1 without any steroid substrate has been reported for this group of reductases 23