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We first confirmed the dynamic profile of the PPP during chondrocyte differentiation by immunohistological staining of glucose-6-phosphate dehydrogenase (G6PDH), the rate-limiting enzyme of the PPP

Neuroglial reactivity, therefore, may indeed be associated with or reflect inflammatory changes in the CNS or mirror inflammation outside the CNS

It is unclear why DMV neurons can tolerate LP, while SNpc DA neurons cannot

Tissue remodeling gene changes may support healthy extracellular matrix maintenance

Graphical Abstract Similar content being viewed by others Introduction Androgens and oestrogens are sex steroid hormones that not only play an essential role in reproductive biology but also regulate energy metabolism in insulin-sensitive tissues [1, 2]

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