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The principal cell type involved in CNS inflammation is the microglia

Diabetes: Oxidative stress due to low glutathione can worsen insulin resistance and contribute to the complications of diabetes such as nerve damage and cardiovascular issues

doi: 10.1002/ptr.3040

Artificial intelligence to deep learning: machine intelligence approach for drug discovery

Clinical trials consistently show NAC raises hepatic glutathione by 2535% within 4 weeks at this dosing

This could be the consequence of a maintenance dose too high for optimal cognitive functioning
