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Finally, it is important to mention that despite the lack of differences between RPM and control-treated cows, clear changes were reported regarding maternal blood parameters, nutrient delivery through the placenta, in addition to positive effects on follicular and fetal development, and offsprings postnatal performance

In the UK, B12 replacement is typically administered via intramuscular hydroxocobalamin injections for patients with confirmed deficiency, particularly those with malabsorption or pernicious anaemia, as specified in the BNF and NICE CKS guidance on B12 and folate deficiency anaemia