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concentrations greater than 60 M were not tested due to known cytotoxic effects in 3T3-L1 cells (see Figure 1)

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As Kannt & Pfenninger highlight in Frontiers in Physiology , maintaining NAD levels is a cornerstone of metabolic health, supporting mitochondrial function and improving resistance to metabolic stress (Kannt & Pfenninger, Frontiers in Physiology )

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