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Description
Blood pressure effects are generally beneficial, with many patients experiencing modest reductions in both systolic and diastolic blood pressure, likely secondary to weight loss and improved metabolic parameters

Limitations 1 : 1 : Results should be interpreted with caution because of the retrospective pre-post design without a control or comparator arm and the relatively short follow-up (6 months) Hypoglycemia may have been underreported, as only the clinically significant events were likely to have been captured (eg, no SMBG or CGM data) EMR database analysis as a potential for selection bias that cannot be controlled, as well as EMR data-capture challenges (eg, coding errors, no dosing data) Patients were mainly from the Northwest and Southern US states and therefore may not be representative of the US national landscape Sanofi-sponsored study *Follow-up period 6 months included GLP-1 RA + Toujeo (N=271)

ACV water recipes: The simplest way to consume vinegar is to mix one to two tablespoons into an eight-ounce glass of filtered water with a dash of lemon juice before meals

In Florida, even a short time in a hot car can expose medication to temperatures above 86F, which may damage the active ingredients

The anorexigenic effect of GLP-1 seems to be transduced via GLP-1R signaling in several areas of the brain, including both hypothalamic nuclei and the hindbrain

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